Searchable abstracts of presentations at key conferences in endocrinology

ea0056p438 | Diabetes complications | ECE2018

Investigation of serum SCUBE-1 level in relation to microvascular complications in patients with type 2 diabetes mellitus

Bingol Umut , Kevser Demir Ayse , Kutluturk Faruk , Cansel Ozmen Zeliha , Demir Osman

Objective: The aim of this study was to investigate the association between serum level of signal peptide-CUB-EGF domain-containing protein 1 (SCUBE-1) and both type 2 diabetes mellitus and its related microvascular complications.Material and methods: The study was included 50 type 2 diabetic patients with complications (group 1), 50 diabetic patients without complications (group 2) and 50 healthy individuals as control group (group 3). Anthropometry and...

ea0099rc6.1 | Rapid Communications 6: Thyroid | Part I | ECE2024

Age-specific reference intervals for TSH and FT4 to optimize diagnosis of thyroid disease

Jansen Heleen , Dirks Niek , Hillebrand Jacquelien , Ten Boekel Edwin , Brinkman Jacoline , Buijs Madelon , Demir Ayse , Dijkstra Ineke , Endenburg Silvia , Engbers Paula , Gootjes Jeannette , Janssen Marcel , Kamphuis Stephan , Kniest-de Jong Wilhelmina , Kruit Adrian , Michielsen Etienne , Wolthuis Albert , van Trotsenburg A.S. Paul , den Heijer Martin , Bruinstroop Eveline , Boelen Anita , Heijboer Annemieke C , den Elzen Wendy

Introduction: Thyroid disorders are generally diagnosed based on thyroid stimulating hormone (TSH) outside the reference interval (RI), and subsequent free thyroxine (FT4) concentrations. Most laboratories do not provide age-specific RIs for TSH and FT4 beyond childhood, although it is known that TSH concentrations vary with age which may be important to take into account. Therefore, we aimed to establish age-specific RIs for TSH and FT4 throughout life using an indirect metho...